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The military researchers contributed greatly to anthrax research, but the mechanism of the toxin wouldn't have been so quickly solved had university labs not gotten involved as well.

[The Best American Science Writing, 2003]

Some did have feelings of hopelessness characterized by an inability to envision a meaningful future given the limits imposed by their disease, but such feelings are often distinct from clinical depression.

(N EnglJ Med May 10, 2007)